Listen To Tom Hamilton’s American Babies Play A Full Bruce Springsteen Set With Aron Magner

first_imgLast night, Tom Hamilton’s American Babies brought their Bruce Springsteen tribute set to The Ardmore Music Hall in Philadelphia, PA. The set, dubbed “Philly is the Boss”, featured special guest Aron Magner of The Disco Biscuits on keys throughout the evening.The show featured an awesome assortment of Springsteen material from throughout the beloved songwriter’s vast catalog. The show kicked off with “Wrecking Ball”, the song Bruce wrote in tribute to the old Giants Stadium, before moving into more classic material like “Badlands”, “The Promised Land”, and “Tenth Avenue Freeze Out”, with “Atlantic City” providing an ultimate sing-a-long moment.The rest of the show was filled with more classic Springsteen material such as “I’m On Fire”, “The Ghost of Tom Joad”, “Born to Run”, “Dancing In The Dark”. Of course, “Glory Days” served as the lone encore, bringing the glorious performance to a close. Listen to the whole show below, courtesy of and taper Keith Litzenberger.Tom Hamilton’s American Babies are currently on the road for a massive two-month fall tour, including special “Masquerade Ball” cover sets sets at The Tonic Room in Chicago, IL on October 29th and at American Beauty in New York City on November 5th. Don’t miss out!last_img read more

LOCKN’ To Host FREE “Here Comes Sunshine” Open House Tomorrow

first_imgWith this year’s LOCKN’ right around the corner, festival organizers are inviting fans and attendees to a special open house-type event dubbed “Here Comes Sunshine” on Saturday, August 5th on-site at the newly named Infinity Downs Farms in Arrington, VA. This FREE event will give a first-look at the various festival upgrades that will be featured on the site, including less walking, more shade, improved sight lines, and more efficient traffic routes, among other upgrades designed to improve the overall festival experience for all attendees.RSVP “HERE COMES SUNSHINE: AN EXCLUSIVE LOCKN’ OPEN HOUSE”The event will also feature hayride tours, food trucks, complimentary beer, and a special “Days Between” celebration in honor of Jerry Garcia, with an unveiling of a full-scale Terrapin Station replica and live DVD screening of Jerry Garcia Band Live at Shoreline (9/1/90) in high-definition and full concert audio later in the evening.Another upgrade featured at this year’s event will be LOCKN’s beloved Garcia’s Forest which will be expanded and include a “Terrapin Station Porch,” showcasing weekend-long attractions, including performances by Holly Bowling, Midnight North, Danny Louis, Nicki Bluhm Band, Jason Crosby, Nicole Atkins Band, Melvin Seals, and much more.Garcia’s Forest will be as transcendent as ever, and will feature a wide range of interactive activities, spanning from weekend yoga to an eagerly anticipated screening of Long Strange Trip, director Amir Bar-Lev’s acclaimed documentary history of the Grateful Dead. More information can be found here.LOCKN’ is celebrating the 40th anniversary of the Grateful Dead’s Terrapin Station in a big way, not only will the festival feature the full-scale Terrapin Station replica, but Bob Weir will join Phil Lesh, The Terrapin Family Band, and Nicki Bluhm for a once-in-a-lifetime performance of the Grateful Dead’s 1977 classic album. Head to the festival website to get your tickets today!last_img read more

Electrical conductor sparks interest

first_imgChemists at Harvard and three other institutions have created a purified version of an organic semiconductor with electrical properties that put it among a small handful of organic compounds and that provides an important proof of concept for a screening process to find new compounds for solar panels.Alán Aspuru-Guzik, associate professor of chemistry and chemical biology, worked with colleagues at Stanford University, Haverford College, and Clark University to identify, synthesize, and characterize the compound. It was based on a compound created several years ago by a team from Japan. The compound, with the tongue-twisting name of dinapthothienothiophene, intrigued Aspuru-Guzik and Haverford colleague Joshua Schrier, who decided to use computers to model several variations and screen them for improved electrical properties.That process resulted in seven candidate compounds, from which they selected one, whose synthesis was originally devised by Sergio Granados-Focil, an assistant professor of chemistry at Clark, and was synthesized in the lab of Zhenan Bao, an associate professor in Stanford’s Chemical Engineering Department. Initial measurements by Bao’s group of the compound’s “hole mobility” — a measure of how quickly electrons move analogous to current in a metallic material — showed it was among a small handful of top-performing organic molecules.“It would have taken several years to both synthesize and characterize all the seven candidate compounds. With this approach, we were able to focus on the most promising candidate … as predicted by theory,” Bao said. “This is a rare example of ‘truly rational’ design of new high performance materials.”The Japanese team that created the original compound, led by Kazuo Takimiya, also recently reported that it had created the same compound, though its measurements showed that the compound had lower electrical properties.Though the discovery, reported today in the journal Nature Communications, may have creative applications in electronics, where organic semiconductors are used in thin film transistors and to create extremely thin television screens, Aspuru-Guzik was just as enthusiastic that it provided confirmation of the screening process, based on computer modeling, that he is using to find new materials for solar panels. Sule Atahan, a postdoctoral fellow working with Aspuru-Guzik, said that the close match between the predicted and measured crystal structures of the compound is key, and that theoretical screening is crucial to identify new materials for clean-energy applications.From a cost standpoint, organic semiconductors still cannot compete with the silicon typically used in photovoltaic panels. But organics — a family of typically large, complex molecules built around a backbone of carbon atoms — have many advantages over rigid, heavy silicon. Organic semiconductors can be used to make flexible display screens and can be sprayed like paint or ink, opening a broad range of applications.If a compound can be identified for use in photovoltaics, Aspuru-Guzik said, it may find applications where the rigid structure and equipment needed for traditional solar panels preclude their use, such as in the developing world, where more than 2 billion people still don’t have access to reliable electricity.To identify such a compound, Aspuru-Guzik several years ago began the Clean Energy Project, a distributed computing effort, conducted in collaboration with the IBM World Community Grid, that uses the surplus computing power of idle desktop machines to screen 2.7 million possible candidates. So far, Aspuru-Guzik said, they’ve identified about 5,000 compounds predicted more than 10 percent efficient at converting sunlight to electricity. Additionally, Aspuru-Guzik and Bao have a joint research project, sponsored by the Stanford Global Climate and Energy Program, to use this approach for accelerating the discovery of high performance organic solar cell materials.When the screening is complete, Aspuru-Guzik said, researchers plan to publish a list of the 1,000 most promising compounds. After that will come the labor-intensive process of making them and checking for properties that improve on materials used in solar panels today.“We need only one for the world to be happy,” Aspuru-Guzik said.last_img read more

Exercise can ‘clean up’ Alzheimer’s environment

first_img Plotting the demise of Alzheimer’s New study is major test for power of early action Exposure to new activities may delay onset of dementia Environment counts, Alzheimer’s research suggests Choi explained, “We found the key difference was that exercise also turned on the production of brain-derived neurotrophic factor, or BDNF — known to be important for the growth and survival of neurons — which created a more hospitable brain environment for the new neurons to survive. By combining drugs and gene therapy that both induced neurogenesis and increased BDNF production, we were able to successfully mimic the effects of exercise on cognitive function.” Choi is an assistant professor of neurology at Harvard Medical School (HMS).Tanzi added, “The lesson learned was that it is not enough just to turn on the birth of new nerve cells; you must simultaneously ‘clean up’ the neighborhood in which they are being born to make sure the new cells survive and thrive. Exercise can achieve that, but we found ways of mimicking those beneficial cognitive effects by the application of drugs and gene therapy that simultaneously turn on neurogenesis and BDNF production.”In another part of the study, the investigators found that blocking neurogenesis in Alzheimer’s mice shortly after birth led to more pronounced cognitive deficits later in life. “We will next explore whether safely promoting neurogenesis in Alzheimer’s patients will help alleviate the symptoms of the disease and whether doing so in currently healthy individuals earlier in life can help prevent symptoms later on,” said Tanzi, the Joseph P. and Rose F. Kennedy Professor of Neurology at HMS. “We are very excited to now investigate ways of implementing our new findings to more effectively treat and prevent this terrible disease.”Additional co-authors of the Science paper are Enjana Bylykbashi, Zena Chatila, Eunhee Kim, Alexander Rompala, Mary Oram, Caroline Asselin, Jenna Aronson, Can Zhang, Sean Miller, Andrea Lesinski, and Doo Yeon Kim, Genetics and Aging Research Unit, MGH Neurology; Benjamin Pulli and John W. Chen, MGH Radiology; Star W. Lee, Gregory Clemenson, and Fred H. Gage, Salk Institute for Biological Studies; Henriette van Praag, Florida Atlantic University; and Bruce M. Spiegelman, Dana-Farber Cancer Institute.The study was supported with grants from the Cure Alzheimer’s Fund, the JPB Foundation, the Mathers Foundation, the Leona M. and Harry B. Helmsley Charitable Trust, and National Institutes of Health grants R01 MH060009, 1RF1 AG048080-01 and 2R01 AG014713. Related Their experiments showed that AHN could be induced in the model either by exercise or by treatment with drugs and gene therapy that promoted the birth of neural progenitor cells. Behavioral testing on animals revealed limited cognitive benefits in animals in which neurogenesis had been induced pharmacologically and genetically. But animals in which AHN was induced by exercise showed improved cognitive performance and reduced levels of beta-amyloid, the main component of plaques in Alzheimer’s brains.“Although exercise-induced AHN improved cognition in Alzheimer’s mice by turning on neurogenesis, trying to achieve that result by using gene therapy and drugs did not help,” Tanzi said. “That was because newly born neurons, induced by drugs and gene therapy, were not able to survive in brain regions already ravaged by Alzheimer’s pathology, particularly neuroinflammation. So we asked how neurogenesis induced by exercise differs.” A study by a Massachusetts General Hospital (MGH) research team finds that neurogenesis — inducing the production of new neurons — in the brain structure in which memories are encoded can improve cognitive function in a mouse model of Alzheimer’s disease. Their investigation shows that cognition can be blocked by the hostile inflammatory environment in the brains of patients with Alzheimer’s disease and that physical exercise can “clean up” that environment, allowing new nerve cells to survive and thrive and improving cognition in the Alzheimer’s mice.“In our study we showed that exercise is one of the best ways to turn on neurogenesis and then, by figuring out the molecular and genetic events involved, we determined how to mimic the beneficial effects of exercise through gene therapy and pharmacological agents,” said Rudolph Tanzi, director of the Genetics and Aging Research Unit, vice chair of the Department of Neurology, and co-director of the Henry and Allison McCance Center for Brain Health at MGH. Tanzi is the senior author of the paper published in Science.Lead author Se Hoon Choi of the Genetics and Aging Research Unit said, “While we do not yet have the means for safely achieving the same effects in patients, we determined the precise protein and gene targets for developing ways to do so in the future.”Adult neurogenesis — production of new neurons after the embryonic and, in some animals, neonatal periods — takes place in the hippocampus and another brain structure called the striatum. While adult hippocampal neurogenesis is essential to learning and memory, how the process impacts neurodegenerative conditions like Alzheimer’s has not been well understood. The MGH team set out to investigate how impairment of adult hippocampal neurogenesis (AHN) contributed to Alzheimer’s pathology and cognitive function in a mouse model, and whether increasing AHN could reduce symptoms. “It is not enough just to turn on the birth of new nerve cells; you must simultaneously ‘clean up’ the neighborhood in which they are being born …. Exercise can achieve that …” — Rudolph Tanzi, senior author The Daily Gazette Sign up for daily emails to get the latest Harvard news.last_img read more

US Bans WeChat, TikTok Downloads Starting Sunday

first_imgShare:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to email this to a friend (Opens in new window) TikTok / WeChatWASHINGTON – The Commerce Department plans to restrict access to TikTok and WeChat starting Sunday as the Trump administration’s executive orders against the two apps are set to take effect.The Department said Friday that as of Sunday, any moves to distribute or maintain WeChat or TikTok on an app store will be prohibited. Apple and Google didn’t immediately respond to requests for comment.While users who have already downloaded the apps may be able to continue using the software, the restrictions mean updated versions of the apps cannot be downloaded.“The only real change as of Sunday night will be [TikTok users] won’t have access to improved apps, updated apps, upgraded apps or maintenance,” Commerce Secretary Wilbur Ross said Friday morning on Fox Business. The restrictions targeting WeChat are more extensive. Beginning Sunday, it will be illegal to host or transfer internet traffic associated with WeChat, the Department said in a release. The same will be true for TikTok as of Nov. 12, it said.The Trump administration is currently weighing a proposal involving ByteDance, TikTok’s Chinese parent, and Oracle, designed to resolve the administration’s national security concerns related to TikTok; the deadline for a deal is Nov. 12.Further restrictions could still be announced later, including against other apps if they are seen to be used as workarounds.In earlier court filings, the US government suggested that the restrictions on TikTok and WeChat would be limited in scope and not aimed at harming consumers or TikTok’s US employees.TikTok employees will still be able to receive salaries and benefits and to do their day jobs without running afoul of the ban.In a separate filing on Sept. 15, the US government warned that communication over WeChat might be “impaired” as a result of forthcoming policies, but that “users will not be targeted or subject to penalties.”“Today’s actions prove once again that President Trump will do everything in his power to guarantee our national security and protect Americans from the threats of the Chinese Communist Party,” said Ross. “At the President’s direction, we have taken significant action to combat China’s malicious collection of American citizens’ personal data, while promoting our national values, democratic rules-based norms, and aggressive enforcement of U.S. laws and regulations.”last_img read more

Maize Weevil

first_imgDue to the low price when stocks are most abundant, growers typically store grain in bins immediately after harvest. The corn can be stored up to nine months and then sold when prices improve.To make matters worse, maize weevils can complete a new generation in just 25 days. Their maximum rate of increase is a factor of 25, meaning if there are only 25 maize weevils in January, they can reproduce to 625 by February and 15,625 by March, he said. A small weevil that lives inside corn kernels is costing Georgia growers millions of dollars each year. A University of Georgia scientist has teamed up with farmers and county Extension agents to put a stop to the maize weevil, the No. 1 insect pest of stored corn.“The maize weevil’s entire life cycle is centered on one kernel of corn,” said Michael Toews, the UGA entomologist working to control the pest. (Jordan Hill is an intern with the College of Agricultural and Environmental Sciences.) UGA grains agronomist Dewey Lee said maize weevils have been a big problem for corn growers. Lee suggests that growers look for maize weevils around the edges of the field first.“Farmers should harvest the edges of their field and separate that grain from the rest to try and prevent maize weevils from infesting the rest of the crop,” he said.Managing the temperature of the grain inside the corn bins by using aeration can also help by slowing the insect’s life cycle. Keeping the corn bin below 50 degrees will, literally, stop the weevils in their tracks. At those temperatures, the insect can no longer move or develop. But in southern Georgia, it is hard to maintain such a low temperature. To control the pest, Toews is evaluating grain protectants — insecticides that are applied at very low rates (as low as 1 part per million) to prevent maize weevils from eating stored corn. “We are looking at different chemistries to find solutions that are most appropriate for south Georgia and Alabama conditions,” he said.The length of time the insecticides stay active is also important. Some last only a few months, while others can last up to a year. Prior to filling the bins, it is essential that growers thoroughly clean out any old grain and clear vegetation around the outside of the bin where insects could be, he said. Maize weevils are strong fliers and can easily move from spilled grain and residues into the newly harvested crop.center_img The weevil infests the corn in the field and continues to develop after the corn is placed in the grain bin for storage. A female maize weevil chews a hole and then lays an egg inside the kernel. She seals the egg in the kernel so that it’s hidden from view, making detection difficult. When the egg hatches, the young, hungry weevil starts eating away at the valuable commodity. An adult weevil emerges at the end of the life cycle and chews its way out of the kernel.“There is only a shell left after a maize weevil completes development,” Toews said. “Losses up to 10 percent can occur as result of maize weevils.” “Growers should take advantage of any cool spells during September and October,” Toews said. “Get the grain cooled as quickly as possible.” According to the UGA Center for Agribusiness and Economic Development, Georgia’s farm gate value for corn was more than $510 million in 2013.last_img read more

Moran introduces NAFCU-backed reg relief bill in Senate

first_img continue reading » NAFCU supports legislation introduced Tuesday by Sen. Jerry Moran, R-Kan., which would provide regulatory relief for small financial institutions, including credit unions.S. 1002, the “Community Lending Enhancement and Regulatory Relief (CLEARR) Act,” is companion legislation to H.R. 2133, introduced in the House last week by House Financial Services Subcommittee on Financial Institutions and Consumer Credit Chairman Blaine Luetkemeyer, R-Mo.Sen. Jon Tester, D-Mont., is the lead Democrat on the bill and Sens. Thom Tillis, R-N.C., and Heidi Heitkamp, D-N.D., are original cosponsors.“NAFCU appreciates Sen. Moran’s leadership on this issue and for understanding the high price the current regulatory burden is having on the nation’s smaller financial institutions, including credit unions,” said NAFCU President and CEO Dan Berger. “We look forward to working with members in the both the Senate and the House to advance this important regulatory relief legislation.” 10SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblrlast_img read more

Messi €700m buyout clause at Barcelona still active – La Liga

first_img Loading… Lionel Messi’s €700million release clause in Barcelona contract remains valid and must be paid for his deal to be terminated unilaterally, LaLiga has revealed. Messi has informed Barca he wants to leave the club and he is thought to have not attended pre-season medical tests with the rest of the first team on Sunday. According to reports, the Argentina star believes the clause in his contract that allows him to terminate it at the end of each season – and thereby become a free agent – still applies because 2019-20 was extended to August due to the coronavirus pandemic. However, Barcelona appear adamant this clause has long since expired and that the player’s €700m buyout option must be paid if he is to be released. In a statement issued on Sunday, LaLiga insisted Messi’s contract can only be terminated by the player if the release clause is paid in full. The LaLiga statement said: “The contract is currently in force and contains a ‘termination clause’ applicable in the event that Lionel Andres Messi decides to urge the early unilateral termination of the contract, carried out in accordance with article 16 of royal decree 1006/1985, of June 26, by which the special employment relationship of professional athletes is regulated.Advertisement “In compliance with the applicable regulations, and following corresponding procedure in these cases, LaLiga will not carry out the process for a player to be de-registered from the federation unless they have previously paid the amount of said clause.” Messi is reportedly determined to leave Barca, the club he joined as a 13-year-old, but any move would be complicated by the need for a suitor to pay a transfer fee. Promoted Content8 Ways Drones Will Automate Our FuturePortuguese Street Artist Creates Hyper-Realistic 3D GraffitiTop 10 Disney Male Role Models20 Completely Unexpected Facts About ‘The Big Bang Theory’Which Country Is The Most Romantic In The World?5 Of The World’s Most Unique Theme ParksThe Best Cars Of All Time7 Worst Things To Do To Your Phone7 Black Hole Facts That Will Change Your View Of The Universe7 Ways To Understand Your Girlfriend BetterNothing Compares To Stargazing Places Around The World7 Theories About The Death Of Our Universe Read Also: VIDEO: Lyon beats Wolfsburg for fifth straight Women’s UCL Manchester City, Inter, Paris Saint-Germain and Juventus are said to be the most likely to sign him, but his substantial wages present a major obstacle in negotiations even before a transfer fee is considered. Although Barca would be unlikely to hold out for €700m, they are likely to demand at least a nine-figure fee, even though Messi’s contract expires in under a year. FacebookTwitterWhatsAppEmail分享 last_img read more

Salina Speedway set for opening night this Friday

first_imgBy John Lowery SALINA, Kan. – It’s been a long off season for many tracks. Salina Speedway is one of those tracks that spent the off-season working hard to make racing experience better for both the racers and the fans. This Friday night, April 25, all of the hard work in the off season will pay off as the first of 24 dates kicks off just after 7:15 p.m. Salina Speedway hosts the best of the best when it comes to dirt track racing on a weekly basis. There are seven classes that comprise the weekly show:BMS IMCA Modifieds, M&H Motors IMCA Northern Sport Mods, Budweiser IMCA Hobby Stocks BSB Manufacturing Late Models, sanctioned by the Nesmith Crate Late Model Series in 2014, Coors Light Street Stocks, AutoHouse Towing Mod Lites and the T&R Dirt Construction Mini Stocks. Each division will battle it out every week to see who can end up in the Xtreme Motorsports Victory Lane.The class of race cars aren’t the only attractions at Salina Speedway, as the drivers add just as much character. All 2013 champions will be back to defend their titles this season. Delbert Smith will be ready to take on any and all comers in the Late Model division, Joe Cleveland, the two-time defending champion, is ready to defend his hard-fought IMCA Modified championship, one of the toughest competitors around is Tyler Frye in the Northern SportMods and Mike Trasowsky will see plenty of competition as he tries to repeat in the IMCA Hobby Stock class. Duane Toyne, Justin Kinderknecht and Brian Dunsworth are other returning champions that will look for another title. Each champion will find the going tough in 2014 as the competition has gotten stronger since a year ago. Salina Speedway has made a lot of track improvements in the off season that will be evident on opening night, but the fans might be hoping for a new promotion to be put into effect every single race night.Beginning in 2014 if there are 1,500 fans in attendance on a given race night the following week fans will be given half priced admission. That means $5 will get you into see the greatest show on dirt. In this tough economy, promoter Tommy Hendrickson and his staff wanted to go above and beyond to help the fans out. This promotion should get everyone fired up about saving money and getting to see great racing. This is only the first promotion of the year, fans will have to wait and see what will follow this one. Hendrickson didn’t forget the racers this season either as he put together the Scoggin-Dickey Chevrolet Crate Challenge for drivers competing in the three IMCA divisions. A driver who races the entire season minus one race for 2014 season will be eligible to win a free 604 crate motor (Modifieds) or a free 602 crate motor (Northern SportMods/Hobby Stocks) to be given away at the year end banquet. The drivers who win the crate motors will also have to be at the banquet but that is a small price to pay for taking home a brand new power plant!Racing action gets started Fridays with hot laps at 7:15 p.m. and the racing action goes green shortly after the completion of hot laps.Ticket prices are $10 for adults and seniors 55 and over are just $5. All active and retired military personnel get into the grandstand free as do kids 15 and under when accompanying a paid adult. Fans wanting to get the 411 on Salina Speedway just need to stay logged in t0 As fans visit the site take a look at the 2014 schedule to see what classes are running, great stories and results and sign up for the text a email blasts. You can also like the Facebook page at or follow on Twitter @SalinaSpeedway1. Salina Speedway is located at 2841 South Burma Road, Salina, Kan., 67401. If you more questions or would like to see about becoming more involved at Salina Speedway call 785 292-9220.last_img read more

Fantastic Fairy bows out

first_img Press Association The six-times Group One winner, who landed last year’s Irish Champion Stakes and the 2010 Irish Oaks, suffered a tendon injury during a workout on Tuesday morning. Dunlop said: “It is with much sadness that a decision was made this morning to retire Snow Fairy. Unfortunately, after a routine piece of fast work, she was found to have re-injured her near fore tendon, which has caused her problems in the last two years. Snow Fairy will head to the breeding sheds in Ireland after Ed Dunlop called time on the brilliant mare’s career.center_img “I would like to take this opportunity to personally thank Mrs (Cristina) Patino for all she has done, she has been the most wonderful owner of a truly amazing horse. “Most owners would have retired her a lot sooner than she did and if this had been the case she would not have won the Irish Champion Stakes last year, which was without doubt her greatest performance. “I would also like to thank all of my staff who have looked after her, ridden her and travelled her around the world. She remains the only international horse to have won two Group Ones in Japan. “Snow Fairy will return to Ireland, where I hope she will have a fantastic life as a broodmare.” Patino’s racing manager Patrick Cooper said: “We’ve had an unbelievable roll. It’s come to an end, but that’s the way it happens. We’ve had some fun along the way. “She will go to Elusive Pimpernel. He is Mrs Patino’s horse and was a very good two-year-old a few seasons back. She will visit him. That will be next year. “She will just be let down. She will stay with Ed for a little while then she will come down to Islanmore Stud in Limerick.” last_img read more